Gumaih, H., AL-Busaili, T., Al-Kabzari, M. (2019). Effects of Qat Water Extract Combined with Sublethal Dose of Cypermethrin on Fetuses Body Weight and Length of Pregnant Mice. Journal of the Advances in Agricultural Researches, 24(3), 370-381. doi: 10.21608/jalexu.2019.163468
Hussein Gumaih; Tawfik Abdelrab AL-Busaili; Mona Ahmed Al-Kabzari. "Effects of Qat Water Extract Combined with Sublethal Dose of Cypermethrin on Fetuses Body Weight and Length of Pregnant Mice". Journal of the Advances in Agricultural Researches, 24, 3, 2019, 370-381. doi: 10.21608/jalexu.2019.163468
Gumaih, H., AL-Busaili, T., Al-Kabzari, M. (2019). 'Effects of Qat Water Extract Combined with Sublethal Dose of Cypermethrin on Fetuses Body Weight and Length of Pregnant Mice', Journal of the Advances in Agricultural Researches, 24(3), pp. 370-381. doi: 10.21608/jalexu.2019.163468
Gumaih, H., AL-Busaili, T., Al-Kabzari, M. Effects of Qat Water Extract Combined with Sublethal Dose of Cypermethrin on Fetuses Body Weight and Length of Pregnant Mice. Journal of the Advances in Agricultural Researches, 2019; 24(3): 370-381. doi: 10.21608/jalexu.2019.163468
Effects of Qat Water Extract Combined with Sublethal Dose of Cypermethrin on Fetuses Body Weight and Length of Pregnant Mice
1Physiology, Biology Department, Faculty of Science, Sana'a Univ., Yemen
2Obstetrics and Gynecology Department, Faculty of Medicine and Health Sciences, Sana’a University
3Obstetrics and Gynecology, Al-Sabain Hospital, Republic of Yemen
4Agricultural Research and Extension Authority (AREA), Dhamar, Yemen
Abstract
The effect of Qat water extract and sublethal concentration of Cypermethrin as active ingredient (A.I.) or formulated type (F) alone or in combination with Qat was evaluated on mice fetuses body weight and length. Female mice were exposed to these treatments during 6th – 18th day of gestation. The results showed that there were significant reductionin mice fetuses body weight and length due to the administration of Qat extract alone, Cypermethrin alone, or the combinations of 5g/kg Qat extract with the respective sublethal dose of 1/10 th LD50 (25 mg/kg) of either insecticide type. The formulated Cypermethrin (F) was more effective than its active ingredient type in all experiments, where the tested commercial formulation of Cypermethrin (Cymbush® 10 % E.C.) showed a dramatic significant reduction in the fetuses body weight and length compared with the control. The reduction of body weight and length was higher in case of Qat extract (5g/kg) + 1/10 th LD50 of Cypermethrin formulation treatment with a mean reduction percentage of 40.00% of fetuses body weight and 59.31% of fetuses body length, while the mean reduction percentages for Cypermethrin (A.I.) were 36.24% and 51.91%, respectively. Qat extract alone had a reduction percentage of 15.07% of fetuses body weight. It could be concluded that there is might be high a risk for those pregnant women who comsume Qat.
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